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| Research Interests: |
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Statistical Genetics/Genomics, Population Genetics,
Bioinformatics, Statistical Quantitative Genetics, Quantitative
Trait Loci (QTL) Mapping, Computational Statistics, Bayesian
Statistics |
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| Selected Publications: |
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Zhu L, Zhang Z, Feng F, Schweitzer P, Phavaphutanon J,
Vernier-Singer M, Corey E, Friedenberg S, Mateescu R, Williams A,
Lust G, Acland G, Todhunter R. ( to appear 2008) Single Nucleotide
Polymorphisms Refine Quantitative Trait Loci Intervals for Hip Joint
Laxity in Dogs. Animal Genetics. |
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Sutter NB, Bustamante CD, Chase K,
Gray MM, Zhao K, Zhu L, Padhukasahasram B, Karlins E, Davis S, Jones
PG, Quignon P, Johnson GS, Parker HG, Fretwell N, Mosher DS, Lawler
DF, Satyaraj E, Nordborg, M, Lark KG, Wayne RK, Ostrander EA.
(2007). A Single IGF1 Allele Is a Major Determinant of Small Size in
Dogs. Science (316): 112 – 115. |
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Hernandez RD, Williamson SH, Zhu L,
Bustamante CD. (2007) Context-Dependent Mutation Rates May Cause
Spurious Signatures of a Fixation Bias Favoring Higher GC-Content in
Humans. Mol Biol Evol. 24(10):2196-2202. |
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Williamson S, Hernandez R, Alon
AF, Zhu L, Nielsen R, and Bustamante CD. (2005) Simultaneous
inference of selection and population growth from patterns of
variation in the human genome. PNAS 102(22):7882-7. |
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Zhu L,
and Bustamante C.D. (2005) A composite likelihood approach for
detecting directional selection from DNA sequence data. Genetics
170: 1411-1421. |
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